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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNA2
All Species:
31.21
Human Site:
Y178
Identified Species:
62.42
UniProt:
P20248
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20248
NP_001228.1
432
48537
Y178
S
V
N
E
V
P
D
Y
H
E
D
I
H
T
Y
Chimpanzee
Pan troglodytes
XP_517420
432
48476
Y178
S
V
N
E
V
P
D
Y
H
E
D
I
H
T
Y
Rhesus Macaque
Macaca mulatta
XP_001100860
432
48504
Y178
S
V
N
E
V
P
D
Y
H
E
D
I
H
T
Y
Dog
Lupus familis
XP_540965
432
48633
Y178
S
V
N
E
V
P
D
Y
H
E
D
I
H
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
P51943
422
47265
Y168
N
V
N
E
V
P
D
Y
Q
E
D
I
H
T
Y
Rat
Rattus norvegicus
Q6AY13
421
47676
Y167
D
V
I
N
V
T
E
Y
A
E
E
I
H
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513040
465
52108
Y209
S
V
N
E
V
P
D
Y
H
E
D
I
H
T
Y
Chicken
Gallus gallus
P43449
395
44062
S144
N
N
V
P
D
Y
V
S
D
I
H
T
Y
L
R
Frog
Xenopus laevis
P47827
415
46651
I164
V
A
D
Y
A
K
E
I
H
T
Y
L
R
E
M
Zebra Danio
Brachydanio rerio
NP_694481
428
47894
Y174
N
V
N
E
V
S
D
Y
A
A
E
I
H
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P14785
491
56134
Y203
R
F
L
E
V
V
Q
Y
Q
M
D
I
L
E
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38819
450
50623
A189
P
L
L
C
C
L
Y
A
P
E
I
H
Y
N
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
91.4
N.A.
85.4
46.5
N.A.
69.2
63.4
57.6
58.7
N.A.
32.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.3
95.3
N.A.
90.9
60.1
N.A.
76.9
72.2
70.3
69.9
N.A.
48.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
46.6
N.A.
100
0
6.6
60
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
60
N.A.
100
13.3
26.6
80
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
9
17
9
0
0
0
0
0
% A
% Cys:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
9
0
59
0
9
0
59
0
0
0
0
% D
% Glu:
0
0
0
67
0
0
17
0
0
67
17
0
0
17
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
50
0
9
9
67
0
9
% H
% Ile:
0
0
9
0
0
0
0
9
0
9
9
75
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
17
0
0
9
0
0
0
0
0
9
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
25
9
59
9
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
9
0
0
9
0
50
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
9
% R
% Ser:
42
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
9
0
9
0
59
0
% T
% Val:
9
67
9
0
75
9
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
9
9
75
0
0
9
0
17
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _